Protocol and Reagents for Pseudotyping Lentiviral Particles with SARS-CoV-2 Spike Protein for Neutralization Assays

SARS-CoV-2 enters cells using its Spike protein, which is also the main target of neutralizing antibodies. Therefore, assays to measure how antibodies and sera affect Spike-mediated viral infection are important for studying immunity. Because SARS-CoV-2 is a biosafety-level-3 virus, one way to simpl...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Katharine H. D. Crawford, Rachel Eguia, Adam S. Dingens, Andrea N. Loes, Keara D. Malone, Caitlin R. Wolf, Helen Y. Chu, M. Alejandra Tortorici, David Veesler, Michael Murphy, Deleah Pettie, Neil P. King, Alejandro B. Balazs, Jesse D. Bloom
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	MDPI AG 2020-05-01
श्रृंखला:	Viruses
विषय:	SARS-CoV-2 COVID-19 coronavirus neutralization assay lentiviral pseudotype Spike
ऑनलाइन पहुंच:	https://www.mdpi.com/1999-4915/12/5/513
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