Characterization of Four Medically Important Toxins from <i>Centruroides huichol</i> Scorpion Venom and Its Neutralization by a Single Recombinant Antibody Fragment

<i>Centruroides huichol</i> scorpion venom is lethal to mammals. Analysis of the venom allowed the characterization of four lethal toxins named Chui2, Chui3, Chui4, and Chui5. scFv 10FG2 recognized well all toxins except Chui5 toxin, therefore a partial neutralization of the venom was observed. Thus...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Hugo Valencia-Martínez, Timoteo Olamendi-Portugal, Rita Restano-Cassulini, Hugo Serrano-Posada, Fernando Zamudio, Lourival D. Possani, Lidia Riaño-Umbarila, Baltazar Becerril
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2022-05-01
Sarja:	Toxins
Aiheet:	affinity maturation kinetic and thermodynamic parameters phage display scFv scorpion toxins
Linkit:	https://www.mdpi.com/2072-6651/14/6/369
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