Of Seven New K⁺ Channel Inhibitor Peptides of <i>Centruroides bonito</i>, α-KTx 2.24 Has a Picomolar Affinity for Kv1.2

Seven new peptides denominated CboK1 to CboK7 were isolated from the venom of the Mexican scorpion <i>Centruroides bonito</i> and their primary structures were determined. The molecular weights ranged between 3760.4 Da and 4357.9 Da, containing 32 to 39 amino acid residues with three putative disulf...

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Detalhes bibliográficos

Principais autores:	Kashmala Shakeel, Timoteo Olamendi-Portugal, Muhammad Umair Naseem, Baltazar Becerril, Fernando Z. Zamudio, Gustavo Delgado-Prudencio, Lourival Domingos Possani, Gyorgy Panyi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-08-01
Colecção:	Toxins
Assuntos:	CboK scorpion toxin <i>Centruroides bonito</i> Kv1.2 Kv1.3 Kv1.2 channelopathies
Acesso em linha:	https://www.mdpi.com/2072-6651/15/8/506
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