Enhancement of Protein–Protein Interactions by Destabilizing Mutations Revealed by HDX-MS
Enhancing protein–protein interactions is a key therapeutic strategy to ensure effective protein function in terms of pharmacokinetics and pharmacodynamics and can be accomplished with methods like directed evolution or rationale design. Previously, two papers suggested the possible enhancement of p...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI AG
2025-08-01
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| Col·lecció: | Biomolecules |
| Matèries: | |
| Accés en línia: | https://www.mdpi.com/2218-273X/15/8/1201 |
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