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Peroxisome-derived ether lipids regulate lysosomal exocytosis

Abstract Lysosomes and peroxisomes are essential for cellular homeostasis, yet how their activities are coordinated remains poorly understood. Here, we identify peroxisome-derived ether lipids as key regulators of lysosomal function. A genome-wide CRISPR/Cas9 screen in LYSET-deficient mucolipidosis...

Olles dieđut

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Bibliográfalaš dieđut
Váldodahkkit: Liang Chen, Danielle Henn, Zhongzheng Dong, Jiaxuan Liang, Aleksander Wielenga, Goncalo Vale, Bala Burugula, Junyi Zou, Yamuna Krishnan, Jeffrey G McDonald, Jacob Kitzman, Ming Li
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Springer Nature 2026-05-01
Ráidu:The EMBO Journal
Liŋkkat:https://doi.org/10.1038/s44318-026-00791-3
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