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Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage

Abstract Alternative splicing (AS) contributes to the biological heterogeneity between species, sexes, tissues, and cell types. Many diseases are either caused by alterations in AS or by alterations to AS. Therefore, measuring AS accurately and efficiently is critical for assessing molecular phenoty...

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Príomhchruthaitheoirí: Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2024-06-01
Sraith:Molecular Brain
Ábhair:
Rochtain ar líne:https://doi.org/10.1186/s13041-024-01112-7
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