Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage

Abstract Alternative splicing (AS) contributes to the biological heterogeneity between species, sexes, tissues, and cell types. Many diseases are either caused by alterations in AS or by alterations to AS. Therefore, measuring AS accurately and efficiently is critical for assessing molecular phenoty...

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Hlavní autoři:	Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-06-01
Edice:	Molecular Brain
Témata:	Long-read RNA sequencing Brain Sex Transcript usage Isoform usage
On-line přístup:	https://doi.org/10.1186/s13041-024-01112-7
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