Computational screening of bioactive phytochemicals from Annona muricata (Soursop) as potential modulators of colon adenocarcinoma-associated targets

Introduction: Colon adenocarcinoma (COAD) remains a leading cause of cancer mortality and is strongly associated with inflammation-driven progression. Annona muricata acetogenins have demonstrated anticancer potential, but their molecular mechanisms and therapeutic relevance in COAD remain insuffici...

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Hauptverfasser:	Regina Oghenevwede Golagha, Abidemi Esther Ojo, Daniel Johnson Jemikalajah, Fatimah Oluwakemi Abdussalam, Mayowa Agbi, Aanuoluwapo Alake, Sunmola Adebola, Tolulope Sharon Rumide, Sarah Oghenefure Golagha
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2026-01-01
Schriftenreihe:	In Silico Research in Biomedicine
Schlagworte:	Annona muricata Colon adenocarcinoma ALOX5 inhibitor Acetogenins Molecular docking
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S3050787126003549
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