PTENβ is an alternatively translated isoform of PTEN that regulates rDNA transcription
PTEN is a potent tumour suppressor involved in cell growth, proliferation and survival. Here the authors identify an N-terminal extended isoform of PTEN, termed PTENβ that negatively regulates ribosomal DNA transcription and cell proliferation, expanding the pleiotropic functions of the PTEN family.
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2017-03-01
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| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/ncomms14771 |
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