PTENβ is an alternatively translated isoform of PTEN that regulates rDNA transcription

PTEN is a potent tumour suppressor involved in cell growth, proliferation and survival. Here the authors identify an N-terminal extended isoform of PTEN, termed PTENβ that negatively regulates ribosomal DNA transcription and cell proliferation, expanding the pleiotropic functions of the PTEN family.

Dades bibliogràfiques

Autors principals:	Hui Liang, Xi Chen, Qi Yin, Danhui Ruan, Xuyang Zhao, Cong Zhang, Michael A. McNutt, Yuxin Yin
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2017-03-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/ncomms14771
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