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Suppression of STK11 induces expansion of polymorphonuclear myeloid-derived suppressive cells and activation of immune signaling in breast cancer

Abstract The tumor microenvironment in breast cancer is typically immunosuppressive. Combined neoadjuvant chemotherapy and immunotherapy is the standard of care for high-risk, triple-negative breast cancer patients, but it is not routinely applied to other breast cancer subtypes. Somatic mutation of...

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書誌詳細
主要な著者: Tzu-Hui Wei, Chi-Che Hsieh, Zhu-Jun Loh, Wei-Pang Chung, Kuo-Ting Lee, Yi-Ling Chen, Hui-Ping Hsu, Che-Hung Shen
フォーマット: Artigo
言語:Inglês
出版事項: Springer 2025-10-01
シリーズ:Cancer Immunology, Immunotherapy
主題:
オンライン・アクセス:https://doi.org/10.1007/s00262-025-04189-8
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