Suppression of STK11 induces expansion of polymorphonuclear myeloid-derived suppressive cells and activation of immune signaling in breast cancer

Abstract The tumor microenvironment in breast cancer is typically immunosuppressive. Combined neoadjuvant chemotherapy and immunotherapy is the standard of care for high-risk, triple-negative breast cancer patients, but it is not routinely applied to other breast cancer subtypes. Somatic mutation of...

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Xehetasun bibliografikoak

Egile Nagusiak:	Tzu-Hui Wei, Chi-Che Hsieh, Zhu-Jun Loh, Wei-Pang Chung, Kuo-Ting Lee, Yi-Ling Chen, Hui-Ping Hsu, Che-Hung Shen
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Springer 2025-10-01
Saila:	Cancer Immunology, Immunotherapy
Gaiak:	Breast cancer STK11 CXCL1 Myeloid-derived suppressive cells
Sarrera elektronikoa:	https://doi.org/10.1007/s00262-025-04189-8
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