GLUT1 inhibition by BAY-876 induces metabolic changes and cell death in human colorectal cancer cells

Abstract Background Glucose transporter 1 (GLUT1) is known to play a crucial role in glucose uptake in malignant tumors. GLUT1 inhibitors reportedly exhibit anti-tumor effects by suppressing cancer cell proliferation. BAY-876, a selective GLUT1 inhibitor, has been shown to inhibit tumor growth in ov...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Masato Hayashi, Keishi Nakamura, Shinichi Harada, Mariko Tanaka, Akiko Kobayashi, Hiroto Saito, Toshikatsu Tsuji, Daisuke Yamamoto, Hideki Moriyama, Jun Kinoshita, Noriyuki Inaki
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2025-04-01
Цуврал:	BMC Cancer
Нөхцлүүд:	Colorectal cancer Glucose transporter 1 BAY-876 Apoptosis
Онлайн хандалт:	https://doi.org/10.1186/s12885-025-14141-9
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!