A Novel Microcrystalline BAY-876 Formulation Achieves Long-Acting Antitumor Activity Against Aerobic Glycolysis and Proliferation of Hepatocellular Carcinoma

BAY-876 is an effective antagonist of the Glucose transporter type 1 (GLUT1) receptor, a mediator of aerobic glycolysis, a biological process considered a hallmark of hepatocellular carcinoma (HCC) together with cell proliferation, drug-resistance, and metastasis. However, the clinical application o...

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Príomhchruthaitheoirí:	Hua Yang, Mu-Zi-he Zhang, Hui-wei Sun, Yan-tao Chai, Xiaojuan Li, Qiyu Jiang, Jun Hou
Formáid:	Artigo
Teanga:	Inglês
Foilsithe / Cruthaithe:	Frontiers Media S.A. 2021-11-01
Sraith:	Frontiers in Oncology
Ábhair:	advanced hepatocellular carcinoma glucose transporter type 1 BAY-876 microcrystalline aerobic glycolysis epithelial-mesenchymal transition
Rochtain ar líne:	https://www.frontiersin.org/articles/10.3389/fonc.2021.783194/full
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