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Silencing p75NTR regulates osteogenic differentiation and angiogenesis of BMSCs to enhance bone healing in fractured rats

Abstract Background Fractures heal through a process that involves angiogenesis and osteogenesis but may also lead to non-union or delayed healing. Bone marrow mesenchymal stem cells (BMSCs) have been reported to play a pivotal role in bone formation and vascular regeneration and the p75 neurotrophi...

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Hlavní autoři: Zhifeng Wu, Yongming Yang, Ming Wang
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2024-03-01
Edice:Journal of Orthopaedic Surgery and Research
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On-line přístup:https://doi.org/10.1186/s13018-024-04653-8
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