Uncovering the glutamate carboxypeptidase II microenvironment using a multi-labeling proteomic approach

Abstract Glutamate carboxypeptidase II (GCPII) is a membrane-bound metallopeptidase predominantly expressed in neural and prostatic tissues, with significantly elevated levels in prostate carcinoma that increase with tumor grade. Despite its significance as a target for imaging and therapy in prosta...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Jana Pokorná, Martin Hadzima, Alena Křenková, Joshua D. Smith, Vladimír Šubr, Robin Kryštůfek, Martin Hubálek, Jana Starková, Karolína Šrámková, Tomáš Etrych, Libor Kostka, František Sedlák, Jan Konvalinka, Pavel Šácha
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2025-11-01
Serie:	Scientific Reports
Soggetti:	PSMA Protein proximity labeling iBody HRP µMap Riboflavin
Accesso online:	https://doi.org/10.1038/s41598-025-28826-5
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!