Inhibition of mitochondrial complex III blocks neuronal differentiation and maintains embryonic stem cell pluripotency.

The mitochondrion is emerging as a key organelle in stem cell biology, acting as a regulator of stem cell pluripotency and differentiation. In this study we sought to understand the effect of mitochondrial complex III inhibition during neuronal differentiation of mouse embryonic stem cells. When exp...

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Hlavní autoři:	Sandro L Pereira, Mário Grãos, Ana Sofia Rodrigues, Sandra I Anjo, Rui A Carvalho, Paulo J Oliveira, Ernest Arenas, João Ramalho-Santos
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2013-01-01
Edice:	PLoS ONE
On-line přístup:	http://europepmc.org/articles/PMC3847032?pdf=render
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