Functional characterization of transcription factor motifs using cross-species comparison across large evolutionary distances.
We address the problem of finding statistically significant associations between cis-regulatory motifs and functional gene sets, in order to understand the biological roles of transcription factors. We develop a computational framework for this task, whose features include a new statistical score fo...
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| Principais autores: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2010-01-01
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| Serija: | PLoS Computational Biology |
| Online dostop: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000652&type=printable |
| Oznake: |
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