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The p97 Inhibitor UPCDC-30245 Blocks Endo-Lysosomal Degradation

The diverse modes of action of small molecule inhibitors provide versatile tools to investigate basic biology and develop therapeutics. However, it remains a challenging task to evaluate their exact mechanisms of action. We identified two classes of inhibitors for the p97 ATPase: ATP competitive and...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Feng Wang, Shan Li, Kai-Wen Cheng, William M. Rosencrans, Tsui-Fen Chou
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2022-02-01
Schriftenreihe:Pharmaceuticals
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Online-Zugang:https://www.mdpi.com/1424-8247/15/2/204
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