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The p97 Inhibitor UPCDC-30245 Blocks Endo-Lysosomal Degradation

The diverse modes of action of small molecule inhibitors provide versatile tools to investigate basic biology and develop therapeutics. However, it remains a challenging task to evaluate their exact mechanisms of action. We identified two classes of inhibitors for the p97 ATPase: ATP competitive and...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Feng Wang, Shan Li, Kai-Wen Cheng, William M. Rosencrans, Tsui-Fen Chou
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2022-02-01
Rangatū:Pharmaceuticals
Ngā marau:
Urunga tuihono:https://www.mdpi.com/1424-8247/15/2/204
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