IGF1-mediated mesenchymal-endothelial transition as a potential regulatory target in calcific aortic valve disease

Abstract Background Aortic valve interstitial cells (VICs) are considered a highly plastic heterogeneous mesenchymal cell population. Although previous studies have demonstrated their potential to differentiate into myofibroblasts, osteoblasts, chondrocytes, and adipocytes, their ability to differen...

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Bibliografiset tiedot

Päätekijät:	Binglin Li, Mi Zhou, Jianghong Guo, Tai Kuang, Tao Lyu, Dan Zhu, Xiaoyan Wang
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2025-11-01
Sarja:	BMC Medicine
Aiheet:	Calcific aortic valve disease Mesenchymal-endothelial transition IGF1
Linkit:	https://doi.org/10.1186/s12916-025-04433-z
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