Caffeine use disorder and analgesic dependence in medication-overuse headache: insights into an underrecognized relationship

BackgroundCaffeine plays a dual role in headache disorders, acting as an analgesic adjuvant while potentially contributing to headache chronification. Its relationship with medication-overuse headache (MOH) and the severity of analgesic dependence remains insufficiently characterized. The study aime...

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Autores principales:	Rehab Magdy, Amr Hassan, Mona Hussein, Alaa Elmazny, Osama Yacoub, Mohamed Abdelghaffar, Nourhan Abdelmohsen Taha, Ahmed Essmat, May M. Fayez, Nahla Merghany, Anas Elgenidi, Ahmed Dahshan
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2026-07-01
Colección:	Frontiers in Neurology
Materias:	analgesic dependence caffeine consumption caffeine use disorder medication-overuse headache primary headache disorders
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fneur.2026.1827585/full
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