Caffeine use disorder and analgesic dependence in medication-overuse headache: insights into an underrecognized relationship

BackgroundCaffeine plays a dual role in headache disorders, acting as an analgesic adjuvant while potentially contributing to headache chronification. Its relationship with medication-overuse headache (MOH) and the severity of analgesic dependence remains insufficiently characterized. The study aime...

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Autors principals:	Rehab Magdy, Amr Hassan, Mona Hussein, Alaa Elmazny, Osama Yacoub, Mohamed Abdelghaffar, Nourhan Abdelmohsen Taha, Ahmed Essmat, May M. Fayez, Nahla Merghany, Anas Elgenidi, Ahmed Dahshan
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-07-01
Col·lecció:	Frontiers in Neurology
Matèries:	analgesic dependence caffeine consumption caffeine use disorder medication-overuse headache primary headache disorders
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fneur.2026.1827585/full
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