Functional HER1/HER2-Expressing Murine Tumor Models for Preclinical Evaluation of Targeted Therapies

<b>Background:</b> HER1 and HER2 are critical receptors involved in tumorigenesis and the development of targeted therapies for various carcinomas. However, most antibodies and drugs currently in development do not recognize murine orthologs, which restricts their evaluation in immunocompetent model...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Talia Fundora-Barrios, Amanda R. Hechavarría-Bajuelo, Lisset Chao García, Miguel Angel Gonzalez-Cruz, Najara Gonzalez-Suarez, Gretchen Bergado-Baez, Belinda Sánchez-Ramírez
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-09-01
coleção:	Receptors
Assuntos:	HER1-HER2 tumor biology targeting therapies murine tumor models lentiviral transduction
Acesso em linha:	https://www.mdpi.com/2813-2564/4/4/18
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!