HER3 beyond the canonical paradigm: a versatile signaling hub in oncogenesis and therapeutic resistance
Abstract Background Human epidermal growth factor receptor 3 (HER3/ErbB3) is classically recognized as a kinase-impaired member of the epidermal growth factor receptor (EGFR) family, which can initiate oncogenic signaling by heterodimerizing with family members. However, the emerging drug resistance...
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| Автори: | , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2026-03-01
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| Серія: | Journal of Translational Medicine |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1186/s12967-026-07934-4 |
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