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Effect of structure and composition of cationic liposomes on the delivery of siRNA in vitro and in vivo

This study explores the effects of the modifications of siRNA delivery systems based on cationic liposomes containing the polycationic amphiphile 2 × 3 and lipid-helper DOPE on their ability to deliver therapeutic siRNA in vitro and in vivo. We supplied the core liposome system with lipoconjugates d...

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Bibliografiske detaljer
Principais autores: Daniil V. Gladkikh, Elena V. Shmendel, Darya M. Makarova, Mikhail A. Maslov, Marina A. Zenkova, Elena L. Chernolovskaya
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-09-01
Serier:Frontiers in Pharmacology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2025.1656671/full
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