Succinate-induced macrophage polarization and RBP4 secretion promote vascular sprouting in ocular neovascularization

Abstract Pathological neovascularization is a pivotal biological process in wet age-related macular degeneration (AMD), retinopathy of prematurity (ROP) and proliferative diabetic retinopathy (PDR), in which macrophages (Mφs) play a key role. Tip cell specialization is critical in angiogenesis; howe...

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Autors principals:	Tianyi Shen, Ruoyi Lin, Chengyu Hu, Donghui Yu, Chengda Ren, Tingting Li, Meijiang Zhu, Zhongqi Wan, Tu Su, Yan Wu, Wenting Cai, Jing Yu
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2023-12-01
Col·lecció:	Journal of Neuroinflammation
Matèries:	Choroidal neovascularization Macrophage Oxygen-induced retinopathy Succinate Tip cells
Accés en línia:	https://doi.org/10.1186/s12974-023-02998-1
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