The CHRNA3 rs578776 variant is associated with an intrinsic reward sensitivity deficit in smokers

A compromised brain reward system has been postulated as a key feature of drug dependence. We examined whether several polymorphisms of genes found to regulate nicotinic acetylcholine receptor (nAChR) and dopamine (DA) expression were related to an intrinsic reward sensitivity (IRS) deficit we previ...

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Autores principales:	Jason D. Robinson, Francesco eVersace, Cho Y. Lam, Jennifer A. Minnix, Jeffrey M. Engelmann, Yong eCui, Maher eKaram-Hage, Sanjay S. Shete, Gail E. Tomlinson, Tina T.-L. Chen, David W. Wetter, Charles E. Green, Paul M. Cinciripini
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2013-09-01
Colección:	Frontiers in Psychiatry
Materias:	Genetics Nicotine Smoking Cessation Addiction ERP Cluster analysis
Acceso en línea:	http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00114/full
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