K-Ras Peptide Mimotope Induces Antigen Specific Th1 and B-Cell Immune Responses against G12A-Mutated K-Ras Antigen in Balb/c Mice

<i>KRAS</i> G12A somatic point mutation in adenocarcinomas is categorized clinically as ineligibility criteria for anti-epidermal growth factor receptor (EGFR) monoclonal antibody therapies. In this study, a modified G12A-K-ras epitope (139A) with sequence-specific modifications to improve immunogen...

Full description

Bibliographic Details

Main Authors:	Pui Yan Siak, Kuan Yee Wong, Adelene Ai-Lian Song, Raha Abdul Rahim, Lionel Lian Aun In
Format:	Artigo
Language:	Inglês
Published:	MDPI AG 2021-02-01
Series:	Vaccines
Subjects:	<i>KRAS</i> <i>Lactococcus lactis</i> tetanus toxoid peptide-based vaccine
Online Access:	https://www.mdpi.com/2076-393X/9/3/195
Tags:	Add Tag No Tags, Be the first to tag this record!