Variation in virion phosphatidylserine content drives differential GAS6 binding among closely related flaviviruses

ABSTRACT Many enveloped viruses engage phosphatidylserine (PS) receptors to enter cells, a phenomenon known as “apoptotic mimicry.” We previously reported that Zika virus (ZIKV), but not closely related West Nile virus (WNV) or dengue virus (DENV), utilized AXL to infect cells because only ZIKV coul...

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Principais autores:	Lizhou Zhang, Byoung-Shik Shim, Claire Kitzmiller, Young-Chan Kwon, Audrey Stéphanie Richard, Michael Reynolds Farzan, Hyeryun Choe
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology 2025-10-01
叢編:	Journal of Virology
主題:	flavivirus (ZIKV, DENV, WNV) virus entry phosphatidylserine PS receptor GAS6 AXL
在線閱讀:	https://journals.asm.org/doi/10.1128/jvi.01111-25
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