Variation in virion phosphatidylserine content drives differential GAS6 binding among closely related flaviviruses

ABSTRACT Many enveloped viruses engage phosphatidylserine (PS) receptors to enter cells, a phenomenon known as “apoptotic mimicry.” We previously reported that Zika virus (ZIKV), but not closely related West Nile virus (WNV) or dengue virus (DENV), utilized AXL to infect cells because only ZIKV coul...

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Autors principals:	Lizhou Zhang, Byoung-Shik Shim, Claire Kitzmiller, Young-Chan Kwon, Audrey Stéphanie Richard, Michael Reynolds Farzan, Hyeryun Choe
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology 2025-10-01
Col·lecció:	Journal of Virology
Matèries:	flavivirus (ZIKV, DENV, WNV) virus entry phosphatidylserine PS receptor GAS6 AXL
Accés en línia:	https://journals.asm.org/doi/10.1128/jvi.01111-25
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