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Inhibition of stress resilience and adult hippocampal neurogenesis by platelet-derived LPA16:0 in anxiety

Abstract Anxiety is an aggravating comorbidity of many psychiatric disorders that is often underdiagnosed and undertreated, and little is known on the mechanisms underlying its regulation. Here, we find that serum LPA16:0 abundance increases with trait anxiety in both humans and mice; while high LPA...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Thomas Larrieu, Fabio Grieco, Charline Carron, Marta Vilademunt, Crystal Weber, Kyllian Ginggen, Aurélie Delacrétaz, Hector Gallart-Ayala, Mumeko C. Tsuda, Heather A. Cameron, Chin B. Eap, Julijana Ivanisevic, Pierre Magistretti, Evgenia Salta, Giorgia Tosoni, Dilara Ayyildiz, Ludovic Telley, Alexandre Dayer, Camille Piguet, Nicolas Toni
التنسيق: Artigo
اللغة:Inglês
منشور في: Nature Portfolio 2026-02-01
سلاسل:Nature Communications
الوصول للمادة أونلاين:https://doi.org/10.1038/s41467-026-69240-3
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