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PCIF1, the only methyltransferase of N6,2-O-dimethyladenosine

Abstract N6-methyladenosine(m6A), is the most abundant post-transcriptional modification of mRNA in biology. When the first nucleotide after the m7G cap is adenosine, it is methylated at the N6 position to form N6,2-O-dimethyladenosine (m6Am). m6Am is a reversible modification located at the first t...

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Bibliografiske detaljer
Principais autores: Yuting Wu, Xi Pu, Sihui Wu, Yiran Zhang, Shengqiao Fu, Haowen Tang, Xu Wang, Min Xu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-10-01
Serier:Cancer Cell International
Fag:
Online adgang:https://doi.org/10.1186/s12935-023-03066-7
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