Plasma growth differentiation factor-15 is associated with cardiovascular events in patients hospitalized for acute exacerbation of COPD

Abstract Patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) are at increased risk of major adverse cardiovascular events (MACE) and death. Growth differentiation factor-15 (GDF-15), a marker of cellular stress and inflammation, and Syndecan-1, a marker of endothelial...

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Autori principali:	Pradeesh Sivapalan, Daniel Alexander Ackermann, Anna Kubel Vognsen, Ruth Frikke-Schmidt, Jens P. Goetze, Thérèse Lappere, Christina Christoffersen, Jon Torgny Wilcke, Charlotte S. Ulrik, Niklas Dyrby Johansen, Mats C. Højbjerg Andersen, Alexander G. Mathioudakis, Jørgen Vestbo, Manan Pareek, Tor Biering-Sørensen, Jens-Ulrik Jensen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2026-01-01
Serie:	Scientific Reports
Soggetti:	Biomarker COPD AECOPD Cardiovascular Risk GDF-15 Syndecan-1
Accesso online:	https://doi.org/10.1038/s41598-025-27988-6
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