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Antitumor Efficacy of EGFR-Targeted Recombinant Immunotoxin in Human Head and Neck Squamous Cell Carcinoma

Over 90% of head and neck squamous cell carcinoma (HNSCC) overexpresses the epidermal growth factor receptor (EGFR). However, the EGFR-targeted monotherapy response rate only achieves 10–30% in HNSCC. Recombinant immunotoxin (RIT) often consists of an antibody targeting a tumor antigen and a toxin (...

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Autors principals: Guiqin Xie, Liang Shan, Yuanyi Liu, Tzyy-Choou Wu, Xinbin Gu
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2022-03-01
Col·lecció:Biology
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Accés en línia:https://www.mdpi.com/2079-7737/11/4/486
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