Codice QR

Bioorthogonal Sonodynamic Plug‐and‐Play Targeting Chimeras (SDPTAC) for Precise Targeted Protein Degradation

ABSTRACT Targeted protein degradation (TPD) offers powerful therapeutic opportunities but is limited by poor tissue penetration and E3 ligase dependence. Herein, we develop Sonodynamic Plug‐and‐Play Targeting Chimeras (SDPTAC), an ultrasound (US)‐activated, bioorthogonal strategy for in situ protein...

Descrizione completa

Salvato in:
Autori principali: Yuhan Bao, Yaojin Zhu, Xinhao Wei, Yuxin Fang, Jiayi Zhu, Fei Gao, Guoqiang Dong, Shipeng He, Chunquan Sheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley 2026-02-01
Serie:Advanced Science
Soggetti:
bioorthogonal chemistry
SDPTAC
sonodynamic therapy
targeted protein degradation
Accesso online:https://doi.org/10.1002/advs.202520975
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!

Documenti analoghi