Inhibition of HIV-1 replication by primer RNA packaging inhibitors
ABSTRACT An essential step in the life cycle of human immunodeficiency virus type 1 (HIV-1) is the packaging of tRNA3Lys during viral assembly. This step, which requires the assembly of a ternary complex consisting of GagPol, mitochondrial lysyl-tRNA synthetase, and tRNA3Lys, is essential for the pr...
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| Автори: | , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
American Society for Microbiology
2025-11-01
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| Серія: | mBio |
| Предмети: | |
| Онлайн доступ: | https://journals.asm.org/doi/10.1128/mbio.02087-25 |
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