DREAM target reactivation by core transcriptional regulators supports neuroblastoma growth
Chromosome 17q gains are a common alteration in high-risk neuroblastomas with unknown functional significance. We identified a 17q super-enhancer regulated T-box Transcription Factor 2 (TBX2) as constituent of a core regulatory circuitry driving proliferation through enhancing V-myc myelocytomatosis...
Gardado en:
| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis Group
2019-03-01
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| Series: | Molecular & Cellular Oncology |
| Assuntos: | |
| Acceso en liña: | http://dx.doi.org/10.1080/23723556.2019.1565470 |
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