Increased Xanthine Oxidoreductase Activity in Patients With Systemic Sclerosis-Associated Pulmonary Arterial HypertensionTake-Home Points

Background: Preclinical studies have demonstrated the importance of xanthine oxidoreductase (XOR) in the pathobiology of pulmonary hypertension (PH) through generation of uric acid, reactive oxygen species, and vascular endothelial dysfunction. Research Question: In 2 well-characterized cohorts of p...

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Principais autores:	Julie C. Coursen, MD, Tijana Tuhy, MD, Adrianne Woods, CCRP, Laura K. Hummers, MD, Ami A. Shah, MD, MHS, Paul M. Hassoun, MD, Rachel L. Damico, MD, PhD, Stephen C. Mathai, MD, MHS, Catherine E. Simpson, MD, MHS
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2026-03-01
叢編:	CHEST Pulmonary
主題:	pulmonary arterial hypertension scleroderma
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2949789225000790
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