Increased Xanthine Oxidoreductase Activity in Patients With Systemic Sclerosis-Associated Pulmonary Arterial HypertensionTake-Home Points

Background: Preclinical studies have demonstrated the importance of xanthine oxidoreductase (XOR) in the pathobiology of pulmonary hypertension (PH) through generation of uric acid, reactive oxygen species, and vascular endothelial dysfunction. Research Question: In 2 well-characterized cohorts of p...

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Detalhes bibliográficos

Principais autores:	Julie C. Coursen, MD, Tijana Tuhy, MD, Adrianne Woods, CCRP, Laura K. Hummers, MD, Ami A. Shah, MD, MHS, Paul M. Hassoun, MD, Rachel L. Damico, MD, PhD, Stephen C. Mathai, MD, MHS, Catherine E. Simpson, MD, MHS
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-03-01
coleção:	CHEST Pulmonary
Assuntos:	pulmonary arterial hypertension scleroderma
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2949789225000790
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