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De novo formation of left-right asymmetry by posterior tilt of nodal cilia.

In the developing mouse embryo, leftward fluid flow on the ventral side of the node determines left-right (L-R) asymmetry. However, the mechanism by which the rotational movement of node cilia can generate a unidirectional flow remains hypothetical. Here we have addressed this question by motion and...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2005-08-01
Serie:PLoS Biology
Accesso online:http://dx.doi.org/10.1371/journal.pbio.0030268
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