The impact of p53 mutation on tumor immune evasion: mechanistic insights and clinical implications
Mutant p53(Mtp53) not only loses its canonical tumor-suppressive functions but also acquires oncogenic gain-of-function properties, positioning it as a central orchestrator in reshaping the tumor immune microenvironment. This review systematically delineates how Mtp53 actively establishes and sustai...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Frontiers Media S.A.
2026-02-01
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| Colección: | Frontiers in Immunology |
| Materias: | |
| Acceso en línea: | https://www.frontiersin.org/articles/10.3389/fimmu.2026.1753215/full |
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