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Urolithin A enhances mitochondrial biogenesis-related markers and maximal respiratory capacity during C2C12 differentiation

IntroductionSkeletal muscle differentiation in the C2C12 myoblast model requires extensive mitochondrial remodeling to meet rising bioenergetic demands through coordinated changes in biogenesis, dynamics, and respiratory adaptation. Urolithin A (UA), a gut microbiota-derived metabolite of ellagitann...

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Kaydedildi:
Asıl Yazarlar: Ronald Vargas-Foitzick, Diego Irribarra-Tapia, Mayalen Valero-Breton, Elisa Balboa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2026-06-01
Seri Bilgileri:Frontiers in Cell and Developmental Biology
Konular:
C2C12 myotubes
maximal respiration
myogenic differentiation
oxphos
urolithin A
Online Erişim:https://www.frontiersin.org/articles/10.3389/fcell.2026.1854844/full
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