Klotho enhances bone regenerative function of hPDLSCs via modulating immunoregulatory function and cell autophagy

Abstract Background Human periodontal ligament stem cells (hPDLSCs) have a superior ability to promote the formation of new bones and achieve tissue regeneration. However, mesenchymal stem cells (MSCs) are placed in harsh environments after transplantation, and the hostile microenvironment reduces t...

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Huvudupphov:	Qingru Niu, Huan Chen, Qianmin Ou, Shuqing Yang, Yingying Peng, Yunyi Xie, Le Yu, Zhilan Cheng, Yang Cao, Yan Wang
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	BMC 2023-06-01
Serie:	Journal of Orthopaedic Surgery and Research
Ämnen:	Klotho Human periodontal ligament stem cells (hPDLSCs) Macrophage; Stem cell transplantation Bone regeneration Autophagy
Länkar:	https://doi.org/10.1186/s13018-023-03849-8
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