Klotho enhances bone regenerative function of hPDLSCs via modulating immunoregulatory function and cell autophagy

Abstract Background Human periodontal ligament stem cells (hPDLSCs) have a superior ability to promote the formation of new bones and achieve tissue regeneration. However, mesenchymal stem cells (MSCs) are placed in harsh environments after transplantation, and the hostile microenvironment reduces t...

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Detalhes bibliográficos

Principais autores:	Qingru Niu, Huan Chen, Qianmin Ou, Shuqing Yang, Yingying Peng, Yunyi Xie, Le Yu, Zhilan Cheng, Yang Cao, Yan Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-06-01
coleção:	Journal of Orthopaedic Surgery and Research
Assuntos:	Klotho Human periodontal ligament stem cells (hPDLSCs) Macrophage; Stem cell transplantation Bone regeneration Autophagy
Acesso em linha:	https://doi.org/10.1186/s13018-023-03849-8
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