Are Terminal Alkynes Necessary for MAO-A/MAO-B Inhibition? A New Scaffold Is Revealed

A versatile family of quaternary propargylamines was synthesized employing the KA² multicomponent reaction, through the single-step coupling of a number of amines, ketones, and terminal alkynes. Sustainable synthetic procedures using transition metal catalysts were employed in all cases....

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Panagiou Mavroeidi, Leandros P. Zorba, Nikolaos V. Tzouras, Stavros P. Neofotistos, Nikitas Georgiou, Kader Sahin, Murat Şentürk, Serdar Durdagi, Georgios C. Vougioukalakis, Thomas Mavromoustakos
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2024-05-01
Цуврал:	Molecules
Нөхцлүүд:	propargylamines molecular dynamics MM/GBSA monoaminoxidases
Онлайн хандалт:	https://www.mdpi.com/1420-3049/29/11/2486
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!