Modeling chemotherapy induced neurotoxicity with human induced pluripotent stem cell (iPSC) -derived sensory neurons

Chemotherapy-induced peripheral neuropathy (CIPN) is a frequent, potentially irreversible adverse effect of cytotoxic chemotherapy often leading to a reduction or discontinuation of treatment which negatively impacts patients' prognosis. To date, however, neither predictive biomarkers nor preventive...

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Prif Awduron:	Christian Schinke, Valeria Fernandez Vallone, Andranik Ivanov, Yangfan Peng, Péter Körtvelyessy, Luca Nolte, Petra Huehnchen, Dieter Beule, Harald Stachelscheid, Wolfgang Boehmerle, Matthias Endres
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2021-07-01
Cyfres:	Neurobiology of Disease
Pynciau:	Induced pluripotent stem cell derived sensory neurons (iPSC-DSN) Chemotherapy induced neuropathy 3R Replacement Transcriptome Lithium
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S0969996121001406
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