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The Avidity of Autoreactive Alpha-Synuclein Antibodies in Leucine-Rich Repeat Kinase 2 Mutation Carriers Is Not Altered Compared to Healthy Controls or Patients with Parkinson’s Disease

The accumulation and aggregation of alpha-synuclein (α-Syn) are pathological processes associated with Parkinson’s disease, indicating that the regulation of protein is a crucial etiopathological mechanism. Interestingly, human serum and cerebrospinal fluid contain autoantibodies that recognize α-Sy...

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Principais autores: Alexandra Albus, Yannick Kronimus, Monika Burg-Roderfeld, Hendrik van der Wurp, Dieter Willbold, Tamar Ziehm, Richard Dodel, Jean Alexander Ross
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-08-01
Serier:Biomolecules
Fag:
alpha-synuclein
naturally occurring autoantibodies
Parkinson’s disease
LRRK2
PARK8
Online adgang:https://www.mdpi.com/2218-273X/13/9/1303
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