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Narcissoside attenuates atherosclerosis by suppressing CD36-mediated foam cell formation via upregulation of NR4A1

Abstract Background The formation of foam cells (FCs) is the major contributor to the development of atherosclerosis (AS). Gynostemma pentaphyllum is widely used to treat AS and exhibits biological activity against FCs formation. Narcissoside (Nar) is an important component from G. pentaphyllum flav...

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Principais autores: Ziyuan Wang, Lamei Zhou, Xiaorong Zhang, Zhiren Yao, Yaping Huang, Lei Wang, Ke Pan, Jian Zhang, Hao Zhi, Zhiqi Yin
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-05-01
Serier:Chinese Medicine
Fag:
Atherosclerosis
Narcissoside
Foam cell
CD36
NR4A1
Online adgang:https://doi.org/10.1186/s13020-026-01412-1
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