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Single-cell and spatial analysis reveals the interaction between ITLN1+ foam cells and SPP1+ macrophages in atherosclerosis

IntroductionCardiovascular disease (CVD) caused by atherosclerosis (AS) remains the leading cause of mortality in developed countries. Understanding cellular heterogeneity within the inflammatory microenvironment is crucial for advancing disease management strategies. This study investigates the reg...

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Principais autores: Ying Li, Shanshan Wang, Ruidan Zhang, Yingying Gong, Yulu Che, Kening Li, Zongfu Pan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-02-01
coleção:Frontiers in Cardiovascular Medicine
Assuntos:
atherosclerosis
macrophage
VSMC
foam cells
crosstalk
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1510082/full
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